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ORIGINAL ARTICLE
Year : 2017  |  Volume : 50  |  Issue : 4  |  Page : 119-124

Living donor hepatectomy in female donors with ongoing menstruation: Safety and ethical issues


1 Organ Transplantation Center, China Medical University Hospital; Department of Surgery, China Medical University Hospital; China Medical University, Taichung, Taiwan
2 Organ Transplantation Center, China Medical University Hospital; China Medical University, Taichung, Taiwan
3 China Medical University; Department of Anaesthesiology, China Medical University Hospital, Taichung, Taiwan

Correspondence Address:
Kin-Shing Poon
Organ Transplantation Center, China Medical University Hospital, 2, Yuh-Der Road, Taichung
Taiwan
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/fjs.fjs_42_17

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Purpose: The purpose of this study was to study the safety of the major hepatectomy in female donors with ongoing menstruation in situations where the recipient needs urgent liver transplantation and its impact on menstrual bleeding and subsequent menstrual cycles. Materials and Methods: Fifty-eight female donors that underwent adult-to-adult living donor liver transplantation were enrolled in this study and were categorized into two groups. Group A comprised 49 female donors with normal physiological state and Group B comprised nine female donors with ongoing menstruation during the surgery. All the donors in the cohort underwent right hepatectomy including the middle hepatic vein without any blood transfusion in perioperative period. Results: Preoperative international normalized ratio (INR) in Group A and B was 1.05 ± 0.08 and 1.07 ± 0.08, respectively, while INR at postoperative day 7 in Group A donors was 1.72 ± 0.22 while in Group B donors, it was 1.75 ± 0.26. Perioperative hemoglobin drop in Group A and B was statistically insignificant (1.59 ± 0.83 g% vs 1.68 ± 1.51 g%, P = 0.78). The menstrual blood loss in both the groups was statistically comparable. Conclusions: Our study shows safety of right lobe living donation in female donors with ongoing menstruation with no increased risk of intraoperative excessive bleeding and postoperative physiological impact on their general health.


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