• Users Online: 71
  • Print this page
  • Email this page
REVIEW ARTICLE
Year : 2018  |  Volume : 51  |  Issue : 1  |  Page : 1-8

Treatment strategies for locally advanced rectal cancer with synchronous resectable liver metastasis


Department of Surgery, Division of Colorectal Surgery, Yonsei University College of Medicine, Seoul, Republic of Korea

Correspondence Address:
Prof. Nam Kyu Kim
Department of Surgery, Division of Colorectal Surgery, Yonsei University College of Medicine, 50-1, Yonsei-Ro, Seodaemun-Gu, Seoul 120-752
Republic of Korea
Login to access the Email id

Source of Support: None, Conflict of Interest: None


DOI: 10.4103/fjs.fjs_139_17

Rights and Permissions

Approximately one-third of patients with colorectal cancer are estimated to be diagnosed with synchronous liver metastasis (LM). The only method to get cured is to achieve curative resection for both primary and LM. When it comes to locally advanced rectal cancer with synchronous LM, determination of the treatment strategy for each individual is a quite complex procedure, because it demands sophisticated consideration for both local and systemic control. Timing for the application of systemic chemotherapy (CTx), determination of a chemotherapeutic agent, radiation dose and fractions, and sequencing of preoperative treatment and surgeries are all essential components for establishing optimal treatment strategies for the patients with this disease. In this article, treatment strategies proposed in the literature will be reviewed in the light of oncologic outcomes and treatment toxicity with their possible advantages and disadvantages. Owing to a lack of concrete evidences for the best strategy, this article can guide authors to a better way of determining more tailored treatment for each individual.


[FULL TEXT] [PDF]*
Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)
 

 Article Access Statistics
    Viewed570    
    Printed96    
    Emailed0    
    PDF Downloaded109    
    Comments [Add]    

Recommend this journal