• Users Online: 61
  • Print this page
  • Email this page
ORIGINAL ARTICLE
Year : 2019  |  Volume : 52  |  Issue : 4  |  Page : 127-132

How to differentiate abdominal wall leiomyomas from desmoid tumors?


1 Department of Plastic and Reconstructive Surgery, Chang Gung Memorial Hospital; College of Medicine, Chang Gung University, Taoyuan, Taiwan
2 College of Medicine, Chang Gung University; Department of Internal Medicine, Division of Hematology-Oncology, Chang Gung Memorial Hospital, Taoyuan, Taiwan
3 College of Medicine, Chang Gung University; Department of Pathology, Chang Gung Memorial Hospital, Taoyuan, Taiwan
4 College of Medicine, Chang Gung University; Department of Medical Imaging and Intervention and Chang Gung Memorial Hospital, Taoyuan, Taiwan
5 Department of Plastic and Reconstructive Surgery, Chang Gung Memorial Hospital; College of Medicine, Chang Gung University, Taoyuan, Taiwan; Department of Plastic and Reconstructive Surgery, University of Washington Medical Center, Seattle, USA
6 College of Medicine, Chang Gung University; Department of Rehabilitation, Chang Gung Memorial Hospital, Taoyuan, Taiwan
7 College of Medicine, Chang Gung University, Taoyuan; Department of Obstetrics and Gynecology, Chang Gung Memorial Hospital, Keelung, Taiwan

Correspondence Address:
Prof. Chih-Hung Lin
Department of Plastic and Reconstructive Surgery, Chang Gung Memorial Hospital, Chia-Yi Branch, No. 6, West Chia-Pu Road, Putz, Chia-Yi
Taiwan
Login to access the Email id

Source of Support: None, Conflict of Interest: None


DOI: 10.4103/fjs.fjs_115_18

Rights and Permissions

Background: Desmoid tumor and leiomyoma are abdominal wall tumors with similar clinical, radiographic, and histological features. However, differentiation between these two diseases is important because each may be linked to different systemic diseases, and their managements are entirely different. We proposed that misdiagnosis is possible in some cases. Patients and Methods: Between 1983 and 2010, patients with a history of uterine surgeries and diagnosed with either abdominal wall desmoid tumors or leiomyomas were studied. All the images reviewed by an independent radiologist and surgical specimen were reexamined by immunohistochemistry (IHC) techniques as a standard method to confirm the diagnoses. Results: Fifteen female patients (desmoid tumors, n = 10; leiomyomas, n = 5) were included. The diagnosis of IHC revealed that two cases initially thought to be leiomyomas were desmoid tumors, whereas the remaining 13 cases maintained their initial diagnoses. The accuracy of hematoxylin and eosin staining was 86.7%. All tumors excised without complications, except for one desmoid tumor that recurred and underwent another excision. Conclusion: Preoperative magnetic resonance imaging (MRI) can be considered to differentiate the two diseases, as well as the elimination of other associated systemic diseases should be performed routinely. If MRI is inaccessible or unavailable, preoperative fine-needle biopsy is recommended. Optional IHC staining is required if the primary histological assessment is equivocal or inconclusive.


[FULL TEXT] [PDF]*
Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)
 

 Article Access Statistics
    Viewed135    
    Printed19    
    Emailed0    
    PDF Downloaded28    
    Comments [Add]    

Recommend this journal